Frs2 conditional Knockout mouse

Target

Gene symbol :

Frs2

NCBI gene ID :

327826

Gene full name :

Fibroblast growth factor receptor substrate 2

Synonym :

Frs2a

Protein function

Protein name :

FRS2α

Adapter protein in FGFR signaling pathways

Expected phenotype

KO results in embryonic lethality and FGFR signaling defects

Human disease relevance

Associated with oncogenic FGFR signaling in cancers

Model applications

Model for FGFR signaling and developmental biology

Keywords:

FGFR, MAPK pathway, Development, Signal transduction

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Frs2

conditional Knockout mouse

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