Target

Gene symbol :  
Fstl1
NCBI gene ID :  
14314
Gene full name :  
Follistatin like 1
Synonym :  
Tsc36, Follistatin-like

Protein function

Protein name :  
Follistatin-like protein 1
Secreted glycoprotein modulating BMP and TGF-beta signaling, involved in inflammation, tissue repair, and development

Expected phenotype

Perinatal lethality in null mice, defects in lung and skeletal development, altered inflammatory responses

Human disease relevance

Cardiovascular disease, inflammatory disorders, fibrosis

Model applications

Developmental biology, inflammation models

Keywords:

BMP signaling, tissue repair, secreted factor

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Fstl1

conditional Knockout mouse

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