Gar1 conditional Knockout mouse

Target

Gene symbol :

Gar1

NCBI gene ID :

68147

Gene full name :

GAR1 ribonucleoprotein

Synonym :

Nola1

Protein function

Protein name :

GAR1 protein

Core component of H ACA snoRNPs required for rRNA pseudouridylation and ribosome biogenesis

Expected phenotype

Defective ribosome biogenesis and impaired cell proliferation in functional studies

Human disease relevance

Dyskeratosis congenita, ribosomopathies

Model applications

RNA biology and ribosome assembly models

Keywords:

snoRNP, rRNA modification

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gar1

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe