Target

Gene symbol :  
Gatad2b
NCBI gene ID :  
229542
Gene full name :  
GATA zinc finger domain containing 2B
Synonym :  
P66beta, GATAD2B protein

Protein function

Protein name :  
GATA zinc finger domain-containing protein 2B
Subunit of the NuRD chromatin remodeling complex, regulates transcription and chromatin structure

Expected phenotype

Neurodevelopmental defects and altered gene regulation in loss-of-function models

Human disease relevance

Intellectual disability, neurodevelopmental disorders

Model applications

Chromatin regulation and neurodevelopment models

Keywords:

NuRD complex, chromatin remodeling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Gatad2b

conditional Knockout mouse

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