Gfm1 conditional Knockout mouse

Target

Gene symbol :

Gfm1

NCBI gene ID :

28030

Gene full name :

G elongation factor mitochondrial 1

Synonym :

Efg1

Protein function

Protein name :

Mitochondrial elongation factor G1

Mitochondrial translation elongation factor required for translocation step during protein synthesis in mitochondria

Expected phenotype

Impaired mitochondrial translation, reduced oxidative phosphorylation, growth and neurological defects in functional studies

Human disease relevance

Combined oxidative phosphorylation deficiency

Model applications

Mitochondrial biology and metabolic disease models

Keywords:

mitochondrial translation, oxidative phosphorylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gfm1

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe