Gldc conditional Knockout mouse

Target

Gene symbol :

Gldc

NCBI gene ID :

104174

Gene full name :

Glycine dehydrogenase decarboxylating

Synonym :

P-protein, GLDC

Protein function

Protein name :

Glycine dehydrogenase

Mitochondrial enzyme of the glycine cleavage system, catalyzes glycine decarboxylation

Expected phenotype

Accumulation of glycine, severe neurological defects in loss-of-function models

Human disease relevance

Non-ketotic hyperglycinemia

Model applications

Metabolic and neurodevelopmental disease models

Keywords:

glycine metabolism, mitochondrial enzyme

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gldc

conditional Knockout mouse

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