Gldc conditional Knockout mouse

Target

Gene symbol :

Gldc

NCBI gene ID :

104174

Gene full name :

Glycine dehydrogenase decarboxylating

Synonym :

P-protein, GLDC

Protein function

Protein name :

Glycine dehydrogenase

Mitochondrial enzyme of the glycine cleavage system, catalyzes glycine decarboxylation

Expected phenotype

Accumulation of glycine, severe neurological defects in loss-of-function models

Human disease relevance

Non-ketotic hyperglycinemia

Model applications

Metabolic and neurodevelopmental disease models

Keywords:

glycine metabolism, mitochondrial enzyme

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gldc

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe