Gna11 conditional Knockout mouse

Target

Gene symbol :

Gna11

NCBI gene ID :

14672

Gene full name :

G protein subunit alpha 11

Synonym :

Gq alpha 11, G alpha 11

Protein function

Protein name :

G protein subunit alpha-11

Alpha subunit of heterotrimeric Gq proteins, activates phospholipase C beta signaling downstream of GPCRs

Expected phenotype

Altered GPCR signaling, cardiovascular and smooth muscle phenotypes

Human disease relevance

Endocrine disorders, cancer

Model applications

GPCR signaling and signal transduction models

Keywords:

Gq signaling, phospholipase C

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gna11

conditional Knockout mouse

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