Target

Gene symbol :  
Gzmd
NCBI gene ID :  
14941
Gene full name :  
Granzyme D
Synonym :  
Grd

Protein function

Protein name :  
Granzyme D
Serine protease expressed by cytotoxic lymphocytes, contributes to target-cell killing and immune defense

Expected phenotype

Altered cytotoxic lymphocyte protease repertoire in knockout models

Human disease relevance

Immune dysregulation, infection response

Model applications

Immunology and cytotoxicity models

Keywords:

cytotoxic lymphocytes, serine protease

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Gzmd

conditional Knockout mouse

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