H6pd conditional Knockout mouse

Target

Gene symbol :

H6pd

NCBI gene ID :

100198

Gene full name :

Hexose-6-phosphate dehydrogenase

Synonym :

H6PD, Hex6pd

Protein function

Protein name :

Hexose-6-phosphate dehydrogenase

Generates NADPH in the endoplasmic reticulum lumen, supports steroid metabolism and redox homeostasis

Expected phenotype

Disrupted glucocorticoid metabolism, altered ER redox balance

Human disease relevance

Cortisone reductase deficiency, metabolic disorders

Model applications

Endocrinology and metabolism models

Keywords:

NADPH metabolism, ER redox

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

H6pd

conditional Knockout mouse

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