Hecw2 conditional Knockout mouse

Target

Gene symbol :

Hecw2

NCBI gene ID :

329152

Gene full name :

HECT E3 ubiquitin ligase WWP2-like 2

Synonym :

Nedd4-like E3 ubiquitin ligase 2, HECTD2

Protein function

Protein name :

HECW2 protein

HECT-type E3 ubiquitin ligase regulating protein turnover and neuronal development

Expected phenotype

Neurodevelopmental defects and altered synaptic function in loss-of-function models

Human disease relevance

Neurodevelopmental disorders, intellectual disability

Model applications

Neurodevelopment and ubiquitin pathway models

Keywords:

ubiquitination, E3 ligase

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Hecw2

conditional Knockout mouse

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