Target

Gene symbol :  
Hgs
NCBI gene ID :  
15239
Gene full name :  
Hepatocyte growth factor-regulated tyrosine kinase substrate
Synonym :  
Hrs

Protein function

Protein name :  
HGS
Involved in endosomal sorting and trafficking of membrane proteins.

Expected phenotype

Impaired receptor downregulation

Human disease relevance

Linked to cancer progression and viral infections.

Model applications

Studies on endosomal trafficking and signal transduction.

Keywords:

Endocytosis, Signal Transduction, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Hgs

conditional Knockout mouse

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