Target

Gene symbol :  
Hipk2
NCBI gene ID :  
15258
Gene full name :  
Homeodomain interacting protein kinase 2
Synonym :  
Nlk2

Protein function

Protein name :  
HIPK2 protein
Serine threonine kinase regulating transcription factors, DNA damage response, and apoptosis

Expected phenotype

Increased tumor susceptibility, defective stress-induced apoptosis

Human disease relevance

Cancer, DNA damage response disorders

Model applications

Signal transduction and cancer biology models

Keywords:

protein kinase, apoptosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Hipk2

conditional Knockout mouse

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