Icos conditional Knockout mouse

Target

Gene symbol :

Icos

NCBI gene ID :

54167

Gene full name :

Inducible T cell costimulator

Synonym :

CD278

Protein function

Protein name :

ICOS protein

Costimulatory receptor required for T cell activation and germinal center responses

Expected phenotype

Impaired T cell help, defective antibody responses

Human disease relevance

Immunodeficiency, autoimmune disease

Model applications

Immunology and adaptive immunity models

Keywords:

T cell costimulation, immune regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Icos

conditional Knockout mouse

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