Target

Gene symbol :  
Ift122
NCBI gene ID :  
81896
Gene full name :  
Intraflagellar transport 122
Synonym :  
Wdr10

Protein function

Protein name :  
IFT122 protein
Core component of the IFT-A complex, required for retrograde ciliary transport and Hedgehog signaling

Expected phenotype

Severe ciliopathy phenotypes, craniofacial and skeletal defects

Human disease relevance

Cranioectodermal dysplasia, ciliopathies

Model applications

Cilia biology and developmental models

Keywords:

intraflagellar transport, primary cilium

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ift122

conditional Knockout mouse

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