Ikbke conditional Knockout mouse

Target

Gene symbol :

Ikbke

NCBI gene ID :

56489

Gene full name :

Inhibitor of nuclear factor kappa B kinase subunit epsilon

Synonym :

IKKepsilon

Protein function

Protein name :

IKK epsilon

Serine threonine kinase activating NF-kappaB and interferon signaling pathways

Expected phenotype

Impaired antiviral responses and altered inflammatory signaling

Human disease relevance

Cancer, autoimmune and inflammatory diseases

Model applications

Innate immunity and inflammatory signaling models

Keywords:

NF-kappaB signaling, interferon response

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ikbke

conditional Knockout mouse

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