Il2rb conditional Knockout mouse

Target

Gene symbol :

Il2rb

NCBI gene ID :

16185

Gene full name :

Interleukin 2 receptor beta chain

Synonym :

Cd122

Protein function

Protein name :

IL-2 receptor beta chain

Shared signaling subunit of IL-2 and IL-15 receptors, required for lymphocyte proliferation and survival

Expected phenotype

Impaired NK and T cell development, immune deficiency

Human disease relevance

Immunodeficiency, immune dysregulation

Model applications

Lymphocyte signaling and cytokine response models

Keywords:

IL-2 IL-15 signaling, lymphocyte activation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Il2rb

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe