Il2rb conditional Knockout mouse

Target

Gene symbol :

Il2rb

NCBI gene ID :

16185

Gene full name :

Interleukin 2 receptor beta chain

Synonym :

Cd122

Protein function

Protein name :

IL-2 receptor beta chain

Shared signaling subunit of IL-2 and IL-15 receptors, required for lymphocyte proliferation and survival

Expected phenotype

Impaired NK and T cell development, immune deficiency

Human disease relevance

Immunodeficiency, immune dysregulation

Model applications

Lymphocyte signaling and cytokine response models

Keywords:

IL-2 IL-15 signaling, lymphocyte activation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Il2rb

conditional Knockout mouse

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