Target

Gene symbol :  
Ino80
NCBI gene ID :  
68142
Gene full name :  
INO80 complex subunit
Synonym :  
INO80 homolog, Ino80 homolog S. cerevisiae

Protein function

Protein name :  
INO80 chromatin remodeling ATPase
ATP-dependent chromatin remodeling enzyme regulating transcription, DNA repair, and replication

Expected phenotype

Embryonic lethality, impaired DNA repair and genome stability

Human disease relevance

Cancer, genomic instability disorders

Model applications

Chromatin remodeling, DNA repair models

Keywords:

chromatin remodeling, ATPase

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ino80

conditional Knockout mouse

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