Target

Gene symbol :  
Ints11
NCBI gene ID :  
71957
Gene full name :  
Integrator complex subunit 11
Synonym :  
CPSF3L

Protein function

Protein name :  
Integrator complex subunit 11
Endonuclease subunit of the Integrator complex required for snRNA processing and transcription regulation

Expected phenotype

Impaired RNA processing and transcriptional regulation

Human disease relevance

Neurodevelopmental disorders, cancer

Model applications

RNA processing, transcription regulation models

Keywords:

Integrator complex, RNA cleavage

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ints11

conditional Knockout mouse

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