Target

Gene symbol :  
Ints12
NCBI gene ID :  
71793
Gene full name :  
Integrator complex subunit 12
Synonym :  
C030025E15Rik

Protein function

Protein name :  
Integrator complex subunit 12
Part of the Integrator complex; involved in 3’ end processing of snRNAs

Expected phenotype

Essential gene; knockout causes embryonic lethality

Human disease relevance

Linked to human growth deficiency syndromes

Model applications

Used in studies of RNA processing and developmental regulation

Keywords:

snRNA processing, Integrator complex, Transcription, Development

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ints12

conditional Knockout mouse

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