Target

Gene symbol :  
Kcne1
NCBI gene ID :  
16509
Gene full name :  
Potassium voltage-gated channel subfamily E regulatory subunit 1
Synonym :  
MinK, Isk

Protein function

Protein name :  
Potassium channel subunit KCNE1
Regulatory beta subunit of voltage-gated potassium channels, modulates cardiac repolarization

Expected phenotype

Cardiac conduction defects, deafness, arrhythmias in knockout mice

Human disease relevance

Long QT syndrome, deafness

Model applications

Cardiac electrophysiology and ion channel models

Keywords:

potassium channel, cardiac rhythm

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Kcne1

conditional Knockout mouse

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