Target

Gene symbol :  
Kcne2
NCBI gene ID :  
246133
Gene full name :  
Potassium voltage-gated channel subfamily E member 2
Synonym :  
MinK-related peptide 1 (MiRP1)

Protein function

Protein name :  
Voltage-gated potassium channel subunit beta MiRP1
Modulates various potassium channels including KCNQ1

Expected phenotype

KO causes cardiac arrhythmias, altered gastric pH

Human disease relevance

Linked to long QT syndrome and gastric abnormalities

Model applications

Model for cardiac electrophysiology and gastric secretion

Keywords:

Potassium channel, Cardiac arrhythmia, Ion transport, Long QT

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Kcne2

conditional Knockout mouse

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