Kdm5c conditional Knockout mouse

Target

Gene symbol :

Kdm5c

NCBI gene ID :

20591

Gene full name :

Lysine demethylase 5C

Synonym :

Jarid1c, Smcx

Protein function

Protein name :

Lysine-specific demethylase 5C

Histone demethylase that removes methyl groups from H3K4me2 and H3K4me3, regulates transcription and chromatin state

Expected phenotype

Neurodevelopmental defects, impaired cognitive function in knockout models

Human disease relevance

X-linked intellectual disability, neurodevelopmental disorders

Model applications

Epigenetics, neurodevelopment models

Keywords:

histone demethylation, chromatin regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Kdm5c

conditional Knockout mouse

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