Kdm6b conditional Knockout mouse

Target

Gene symbol :

Kdm6b

NCBI gene ID :

216850

Gene full name :

Lysine demethylase 6B

Synonym :

Jmjd3

Protein function

Protein name :

Lysine-specific demethylase 6B

Histone demethylase targeting H3K27me3, regulates developmental gene expression and immune responses

Expected phenotype

Developmental defects, impaired immune cell differentiation

Human disease relevance

Cancer, inflammatory disorders

Model applications

Epigenetics and immunology models

Keywords:

histone demethylation, transcription regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Kdm6b

conditional Knockout mouse

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