Target

Gene symbol :  
Klrb1
NCBI gene ID :  
100043861
Gene full name :  
Killer cell lectin-like receptor subfamily B member 1
Synonym :  
Nkrp1, Nkrp1a, Cd161

Protein function

Protein name :  
CD161 antigen
Lectin-like receptor involved in NK cell activation and immune modulation

Expected phenotype

Affects NK cell activity and cytokine production

Human disease relevance

Homolog implicated in autoimmune diseases and cancer immunity

Model applications

Model for NK cell biology, immunoregulation, and inflammation

Keywords:

NK cells, Immune receptor, Lectin-like, Inflammation, Immunotherapy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Klrb1

conditional Knockout mouse

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