Target

Gene symbol :  
Krt74
NCBI gene ID :  
406222
Gene full name :  
Keratin 74
Synonym :  
Hha6, K6irs1

Protein function

Protein name :  
Keratin, type II cytoskeletal 74
Structural protein in hair follicles and inner root sheath

Expected phenotype

Abnormal hair shaft formation; hair loss in mutants

Human disease relevance

Mutations linked to hypotrichosis in humans

Model applications

Used in studies of hair development and skin disorders

Keywords:

Keratin, Hair follicle, Cytoskeleton, Hypotrichosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Krt74

conditional Knockout mouse

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