Krt8 conditional Knockout mouse

Target

Gene symbol :

Krt8

NCBI gene ID :

16691

Gene full name :

Keratin 8

Synonym :

EndoA, CK8

Protein function

Protein name :

Keratin 8

Intermediate filament protein essential for epithelial cell structural integrity and stress resistance

Expected phenotype

Embryonic lethality, epithelial fragility, liver defects in knockout models

Human disease relevance

Liver disease, epithelial disorders, cancer

Model applications

Epithelial biology and cytoskeleton models

Keywords:

intermediate filament, epithelial cells

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Krt8

conditional Knockout mouse

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