Target

Gene symbol :  
Laptm5
NCBI gene ID :  
16792
Gene full name :  
Lysosomal protein transmembrane 5
Synonym :  
LAPTM5, E3

Protein function

Protein name :  
Lysosomal-associated transmembrane protein 5
Lysosomal protein regulating immune receptor turnover and lysosomal degradation pathways

Expected phenotype

Altered immune receptor trafficking, immune dysfunction

Human disease relevance

Immune disorders, cancer

Model applications

Immunology and lysosome function models

Keywords:

lysosome, immune regulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Laptm5

conditional Knockout mouse

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