Target

Gene symbol :  
Limk2
NCBI gene ID :  
16886
Gene full name :  
LIM domain kinase 2
Synonym :  
LIMK-2

Protein function

Protein name :  
LIM domain kinase 2
Serine threonine kinase regulating actin cytoskeleton by phosphorylating cofilin

Expected phenotype

Abnormal actin organization, impaired neuronal development

Human disease relevance

Neurodevelopmental disorders, cancer

Model applications

Cytoskeleton and neurobiology models

Keywords:

actin regulation, kinase

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Limk2

conditional Knockout mouse

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