Lmna conditional Knockout mouse

Target

Gene symbol :

Lmna

NCBI gene ID :

16905

Gene full name :

Lamin A C

Synonym :

Lamin A, Lamin C

Protein function

Protein name :

Lamin A C

Nuclear intermediate filament protein maintaining nuclear structure and regulating gene expression

Expected phenotype

Muscular dystrophy, cardiomyopathy, premature aging phenotypes in mutant mice

Human disease relevance

Emery-Dreifuss muscular dystrophy, progeria, cardiomyopathy

Model applications

Nuclear structure and aging models

Keywords:

nuclear envelope, lamin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Lmna

conditional Knockout mouse

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