Target

Gene symbol :  
Lrrc8d
NCBI gene ID :  
231549
Gene full name :  
Leucine rich repeat containing 8 VRAC subunit D
Synonym :  
LRRC8D

Protein function

Protein name :  
Volume-regulated anion channel subunit LRRC8D
Component of volume-regulated anion channels controlling cell volume homeostasis

Expected phenotype

Altered osmotic regulation and solute transport in functional studies

Human disease relevance

Cancer drug uptake, osmotic disorders

Model applications

Ion transport and cell volume regulation models

Keywords:

ion channel, VRAC

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
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Lrrc8d

conditional Knockout mouse

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