Lyn conditional Knockout mouse

Target

Gene symbol :

Lyn

NCBI gene ID :

17096

Gene full name :

LYN proto-oncogene, Src family tyrosine kinase

Synonym :

p53Lyn, p56Lyn, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog

Protein function

Protein name :

Lyn

Non-receptor tyrosine kinase involved in B-cell receptor signaling and regulation of immune responses.

Expected phenotype

Altered B-cell development, immune deficiencies

Human disease relevance

Associated with autoimmune diseases and leukemia.

Model applications

Studies on immune signaling and autoimmune disorders.

Keywords:

Tyrosine kinase, B-cell signaling, Autoimmunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Lyn

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe