Lyn conditional Knockout mouse

Target

Gene symbol :

Lyn

NCBI gene ID :

17096

Gene full name :

LYN proto-oncogene, Src family tyrosine kinase

Synonym :

p53Lyn, p56Lyn, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog

Protein function

Protein name :

Lyn

Non-receptor tyrosine kinase involved in B-cell receptor signaling and regulation of immune responses.

Expected phenotype

Altered B-cell development, immune deficiencies

Human disease relevance

Associated with autoimmune diseases and leukemia.

Model applications

Studies on immune signaling and autoimmune disorders.

Keywords:

Tyrosine kinase, B-cell signaling, Autoimmunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Lyn

conditional Knockout mouse

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