Malt1 conditional Knockout mouse

Target

Gene symbol :

Malt1

NCBI gene ID :

240354

Gene full name :

Mucosa associated lymphoid tissue lymphoma translocation gene 1

Synonym :

Paracaspase, MLT

Protein function

Protein name :

MALT1 paracaspase

Protease and scaffold protein regulating NF-kappaB activation downstream of immune receptors

Expected phenotype

Impaired lymphocyte activation and immune responses in knockout mice

Human disease relevance

Immunodeficiency, lymphoma

Model applications

Immunology and NF-kappaB signaling models

Keywords:

NF-kappaB signaling, immune activation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Malt1

conditional Knockout mouse

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