Map3k10 conditional Knockout mouse

Target

Gene symbol :

Map3k10

NCBI gene ID :

269881

Gene full name :

Mitogen-activated protein kinase kinase kinase 10

Synonym :

MLK2

Protein function

Protein name :

MAP kinase kinase kinase 10

Activates JNK pathway; involved in neuronal apoptosis and stress signaling

Expected phenotype

KO mice show altered neuronal stress responses

Human disease relevance

Implicated in neurodegeneration and Parkinson’s disease

Model applications

Studied in JNK signaling, neurodegeneration, and apoptosis

Keywords:

MAPK pathway, JNK signaling, Apoptosis, Neurodegeneration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Map3k10

conditional Knockout mouse

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