March5 conditional Knockout mouse

Target

Gene symbol :

March5

NCBI gene ID :

69104

Gene full name :

Membrane associated ring-CH-type finger 5

Synonym :

Mitol, March-V

Protein function

Protein name :

MARCH5 ubiquitin ligase

Mitochondrial E3 ubiquitin ligase regulating mitochondrial dynamics and quality control

Expected phenotype

Abnormal mitochondrial morphology and impaired mitophagy

Human disease relevance

Neurodegenerative diseases

Model applications

Mitochondrial biology and mitophagy models

Keywords:

ubiquitin ligase, mitochondria

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

March5

conditional Knockout mouse

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