Target

Gene symbol :  
Mcf2l
NCBI gene ID :  
17207
Gene full name :  
MCF.2 cell line derived transforming sequence-like
Synonym :  
DBS

Protein function

Protein name :  
Guanine nucleotide exchange factor DBS
Rho guanine nucleotide exchange factor regulating cytoskeleton and cell signaling

Expected phenotype

Altered neuronal morphology and cytoskeletal regulation

Human disease relevance

Neurodevelopmental disorders

Model applications

Cytoskeleton and signal transduction models

Keywords:

Rho GTPase signaling, GEF

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mcf2l

conditional Knockout mouse

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