Target

Gene symbol :  
Med19
NCBI gene ID :  
381379
Gene full name :  
Mediator complex subunit 19
Synonym :  
Med31 (paralog)

Protein function

Protein name :  
Mediator of RNA polymerase II transcription subunit 19
Part of the Mediator complex; bridges transcription factors and RNA polymerase II

Expected phenotype

Essential for transcriptional regulation; KO models are embryonic lethal

Human disease relevance

Involved in cancer-related transcriptional misregulation

Model applications

Used in transcriptional machinery and cancer biology studies

Keywords:

Transcription, Mediator complex, RNA Pol II, Gene regulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Med19

conditional Knockout mouse

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