Target

Gene symbol :  
Mib2
NCBI gene ID :  
76580
Gene full name :  
Mindbomb E3 ubiquitin protein ligase 2
Synonym :  
Mind bomb 2, Skeletrophin

Protein function

Protein name :  
MIB2 ubiquitin ligase
E3 ubiquitin ligase regulating Notch signaling and protein turnover

Expected phenotype

Altered Notch signaling and developmental abnormalities

Human disease relevance

Developmental disorders, cancer

Model applications

Notch signaling and ubiquitination models

Keywords:

ubiquitin ligase, Notch signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mib2

conditional Knockout mouse

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