Mto1 conditional Knockout mouse

Target

Gene symbol :

Mto1

NCBI gene ID :

68291

Gene full name :

Mitochondrial translation optimization 1 homolog

Synonym :

CGI-02

Protein function

Protein name :

MTO1 protein

Involved in mitochondrial tRNA modification, required for proper mitochondrial translation

Expected phenotype

Impaired mitochondrial translation and oxidative phosphorylation defects

Human disease relevance

Mitochondrial disease, cardiomyopathy

Model applications

Mitochondrial translation and metabolic models

Keywords:

mitochondrial tRNA modification

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mto1

conditional Knockout mouse

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