Ncf2 conditional Knockout mouse

Target

Gene symbol :

Ncf2

NCBI gene ID :

17970

Gene full name :

Neutrophil cytosolic factor 2

Synonym :

NOXA2, p67phox

Protein function

Protein name :

p67phox

Component of NADPH oxidase complex; generates reactive oxygen species in immune response.

Expected phenotype

Increased susceptibility to infections, impaired oxidative burst.

Human disease relevance

Mutations cause chronic granulomatous disease.

Model applications

Models for studying immune deficiencies and oxidative stress.

Keywords:

NADPH oxidase, Reactive oxygen species, Immune defense

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Ncf2

conditional Knockout mouse

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