Nfasc conditional Knockout mouse

Target

Gene symbol :

Nfasc

NCBI gene ID :

269116

Gene full name :

Neurofascin

Synonym :

Neurofascin, Nfasc155, Nfasc186

Protein function

Protein name :

Neurofascin cell adhesion molecule

Cell adhesion molecule critical for axon initial segment formation and node of Ranvier organization

Expected phenotype

Severe neurological defects, impaired nerve conduction, early lethality in knockout mice

Human disease relevance

Multiple sclerosis, neuropathies

Model applications

Neurobiology and myelination models

Keywords:

cell adhesion, node of Ranvier

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nfasc

conditional Knockout mouse

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