Nmnat1 conditional Knockout mouse

Target

Gene symbol :

Nmnat1

NCBI gene ID :

66454

Gene full name :

Nicotinamide nucleotide adenylyltransferase 1

Synonym :

NMNAT, PNAT1

Protein function

Protein name :

NMNAT1 enzyme

Catalyzes NAD biosynthesis in the nucleus, essential for energy metabolism and DNA repair

Expected phenotype

Neurodegeneration and retinal defects in mutant mice

Human disease relevance

Leber congenital amaurosis, neurodegeneration

Model applications

NAD metabolism and neurodegeneration models

Keywords:

NAD biosynthesis, metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nmnat1

conditional Knockout mouse

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