Npat conditional Knockout mouse

Target

Gene symbol :

Npat

NCBI gene ID :

244879

Gene full name :

Nuclear protein, ataxia-telangiectasia locus

Synonym :

—

Protein function

Protein name :

Nuclear protein ataxia-telangiectasia locus

Involved in cell cycle regulation; phosphorylated by ATM kinase

Expected phenotype

KO leads to embryonic lethality; essential for cell proliferation

Human disease relevance

Linked to ataxia-telangiectasia–related pathways

Model applications

Studied in DNA damage response and cell cycle control

Keywords:

ATM pathway, Cell cycle, Proliferation, DNA damage

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Npat

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe