Nrp1 conditional Knockout mouse

Target

Gene symbol :

Nrp1

NCBI gene ID :

18186

Gene full name :

Neuropilin 1

Synonym :

Neuropilin, BDCA4

Protein function

Protein name :

Neuropilin-1 receptor

Co-receptor for VEGF and semaphorins, regulates angiogenesis and neuronal guidance

Expected phenotype

Embryonic lethality, vascular and neuronal development defects

Human disease relevance

Cancer, vascular disorders

Model applications

Angiogenesis and neurodevelopment models

Keywords:

VEGF signaling, axon guidance

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nrp1

conditional Knockout mouse

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