Target

Gene symbol :  
Ntrk2
NCBI gene ID :  
18212
Gene full name :  
Neurotrophic tyrosine kinase, receptor, type 2
Synonym :  
TrkB, Trk-B

Protein function

Protein name :  
TrkB
Receptor for BDNF and NT-4; involved in CNS development and synaptic plasticity.

Expected phenotype

Altered feeding behavior, obesity, developmental delays.

Human disease relevance

Associated with obesity, developmental delays, and epilepsy.

Model applications

Studies on neurodevelopment and metabolic disorders.

Keywords:

Neurotrophin receptor, Synaptic plasticity, Obesity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Ntrk2

conditional Knockout mouse

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