Otub1 conditional Knockout mouse

Target

Gene symbol :

Otub1

NCBI gene ID :

107260

Gene full name :

OTU deubiquitinase, ubiquitin aldehyde binding 1

Synonym :

OTU domain containing ubiquitin aldehyde binding 1, Otubain-1

Protein function

Protein name :

OTUB1 deubiquitinase

Deubiquitinating enzyme regulating protein stability and DNA damage response pathways

Expected phenotype

Altered DNA damage signaling and ubiquitin-mediated regulation

Human disease relevance

Cancer, DNA repair disorders

Model applications

Ubiquitin signaling and proteostasis models

Keywords:

deubiquitinase, ubiquitin signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Otub1

conditional Knockout mouse

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