Target

Gene symbol :  
P2rx2
NCBI gene ID :  
231602
Gene full name :  
Purinergic receptor P2X 2
Synonym :  
P2X2, P2X purinoceptor 2

Protein function

Protein name :  
P2X2 ATP-gated ion channel
Ligand-gated ion channel activated by extracellular ATP, involved in neuronal signaling

Expected phenotype

Hearing impairment and altered synaptic transmission in knockout mice

Human disease relevance

Hearing loss, neurological disorders

Model applications

Neurobiology and sensory signaling models

Keywords:

purinergic receptor, ATP-gated channel

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

P2rx2

conditional Knockout mouse

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