Pafah1b1 conditional Knockout mouse

Target

Gene symbol :

Pafah1b1

NCBI gene ID :

18472

Gene full name :

Platelet activating factor acetylhydrolase 1b regulatory subunit 1

Synonym :

Lis1

Protein function

Protein name :

LIS1 protein

Regulates dynein-mediated intracellular transport and neuronal migration

Expected phenotype

Severe neuronal migration defects and cortical disorganization

Human disease relevance

Lissencephaly, neurodevelopmental disorders

Model applications

Neurodevelopment and neuronal migration models

Keywords:

neuronal migration, dynein regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pafah1b1

conditional Knockout mouse

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