Target

Gene symbol :  
Pcsk1
NCBI gene ID :  
18548
Gene full name :  
Proprotein convertase subtilisin kexin type 1
Synonym :  
PC1, PC3

Protein function

Protein name :  
Proprotein convertase 1
Protease that cleaves prohormones into active peptide hormones

Expected phenotype

Severe endocrine defects, impaired hormone processing

Human disease relevance

Obesity, endocrine disorders

Model applications

Endocrinology and hormone processing models

Keywords:

prohormone processing, protease

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pcsk1

conditional Knockout mouse

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