Target

Gene symbol :  
Pgd
NCBI gene ID :  
110208
Gene full name :  
Phosphogluconate dehydrogenase
Synonym :  
0610042A05Rik

Protein function

Protein name :  
6-phosphogluconate dehydrogenase
Oxidative pentose phosphate pathway enzyme producing NADPH

Expected phenotype

Redox imbalance and metabolic stress sensitivity when impaired

Human disease relevance

Metabolic disorders and cancer metabolism

Model applications

Model for pentose phosphate pathway and redox biology

Keywords:

Pentose phosphate pathway, NADPH, Redox, Metabolism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pgd

conditional Knockout mouse

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