Pik3c3 conditional Knockout mouse

Target

Gene symbol :

Pik3c3

NCBI gene ID :

225326

Gene full name :

Phosphatidylinositol 3-kinase catalytic subunit type 3

Synonym :

Vps34

Protein function

Protein name :

PI3K class III catalytic subunit VPS34

Lipid kinase producing phosphatidylinositol 3-phosphate, essential for autophagy and vesicle trafficking

Expected phenotype

Embryonic lethality, impaired autophagy and vesicle transport

Human disease relevance

Neurodegeneration, cancer

Model applications

Autophagy and vesicular trafficking models

Keywords:

phosphoinositide signaling, autophagy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pik3c3

conditional Knockout mouse

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